Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions

SARS-CoV-2 is the cause of a pandemic with growing global mortality. Using comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS), we identified 309 host proteins that bind the SARS-CoV-2 RNA during active infection. Integration of this data with ChIRP-MS data from thre...

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Udgivet i:Cell
Main Authors: Flynn, Ryan A., Belk, Julia A., Qi, Yanyan, Yasumoto, Yuki, Wei, Jin, Alfajaro, Mia Madel, Shi, Quanming, Mumbach, Maxwell R., Limaye, Aditi, DeWeirdt, Peter C., Schmitz, Cameron O., Parker, Kevin R., Woo, Elizabeth, Chang, Howard Y., Horvath, Tamas L., Carette, Jan E., Bertozzi, Carolyn R., Wilen, Craig B., Satpathy, Ansuman T.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951565/
https://ncbi.nlm.nih.gov/pubmed/33743211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.03.012
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