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Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions

SARS-CoV-2 is the cause of a pandemic with growing global mortality. Using comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS), we identified 309 host proteins that bind the SARS-CoV-2 RNA during active infection. Integration of this data with ChIRP-MS data from thre...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Flynn, Ryan A., Belk, Julia A., Qi, Yanyan, Yasumoto, Yuki, Wei, Jin, Alfajaro, Mia Madel, Shi, Quanming, Mumbach, Maxwell R., Limaye, Aditi, DeWeirdt, Peter C., Schmitz, Cameron O., Parker, Kevin R., Woo, Elizabeth, Chang, Howard Y., Horvath, Tamas L., Carette, Jan E., Bertozzi, Carolyn R., Wilen, Craig B., Satpathy, Ansuman T.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951565/
https://ncbi.nlm.nih.gov/pubmed/33743211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.03.012
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