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Insights into epithelial cell senescence from transcriptome and secretome analysis of human oral keratinocytes

Senescent cells produce chronic inflammation that contributes to the diseases and debilities of aging. How this process is orchestrated in epithelial cells, the origin of human carcinomas, is poorly understood. We used human normal oral keratinocytes (NOKs) to elucidate senescence programs in a prot...

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Publicat a:Aging (Albany NY)
Autors principals: Schwartz, Rachael E., Shokhirev, Maxim N., Andrade, Leonardo R., Gutkind, J. Silvio, Iglesias-Bartolome, Ramiro, Shadel, Gerald S.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7950289/
https://ncbi.nlm.nih.gov/pubmed/33601339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202658
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