A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells

Normal hair growth occurs in cycles, comprising growth (anagen), cessation (catagen) and rest (telogen). Upon aging, the initiation of anagen is significantly delayed, which results in impaired hair regeneration. Hair regeneration is driven by hair follicle stem cells (HFSCs). We show here that aged...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Tiwari, Rajiv L., Mishra, Pratibha, Martin, Nicola, George, Nikhil Oommen, Sakk, Vadim, Soller, Karin, Nalapareddy, Kodandaramireddy, Nattamai, Kalpana, Scharffetter-Kochanek, Karin, Florian, Maria Carolina, Geiger, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
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Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7950224/
https://ncbi.nlm.nih.gov/pubmed/33629967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202694
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