Φορτώνει......
SIRT1 stabilizes extrachromosomal gene amplification and contributes to repeat-induced gene silencing
Sirtuin 1 (SIRT1) is a protein deacetylase that maintains genome stability by preventing the activation of latent replication origins. Amplified genes in cancer cells localize on either extrachromosomal double minutes (DMs) or the chromosomal homogeneously staining region. Previously, we found that...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Biol Chem |
|---|---|
| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2021
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7949162/ https://ncbi.nlm.nih.gov/pubmed/33539925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100356 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|