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Repeat induces not only gene silencing, but also gene activation in mammalian cells
Repeat-induced gene silencing (RIGS) establishes the centromere structure, prevents the spread of transposons and silences transgenes, thereby limiting recombinant protein production. We previously isolated a sequence (B-3-31) that alleviates RIGS from the human genome. Here, we developed an assay s...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7313748/ https://ncbi.nlm.nih.gov/pubmed/32579599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235127 |
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