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Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells
We demonstrate that convergent transcription induces transcriptional gene silencing (TGS) in trans for both fission yeast and mammalian cells. This methodology has advantages over existing strategies to induce gene silencing. Previous studies in fission yeast have characterized TGS as a cis specific...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504457/ https://ncbi.nlm.nih.gov/pubmed/23022730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2392 |
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