Dicer is required for chromosome segregation and gene silencing in fission yeast cells

RNA interference is a form of gene silencing in which the nuclease Dicer cleaves double-stranded RNA into small interfering RNAs. Here we report a role for Dicer in chromosome segregation of fission yeast. Deletion of the Dicer (dcr1(+)) gene caused slow growth, sensitivity to thiabendazole, lagging...

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Bibliografiske detaljer
Main Authors: Provost, Patrick, Silverstein, Rebecca A., Dishart, David, Walfridsson, Julian, Djupedal, Ingela, Kniola, Barbara, Wright, Anthony, Samuelsson, Bengt, Rådmark, Olof, Ekwall, Karl
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC139198/
https://ncbi.nlm.nih.gov/pubmed/12482946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212633199
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