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Local Myo9b RhoGAP activity regulates cell motility

To migrate, cells assume a polarized morphology, extending forward with a leading edge with their trailing edge retracting back toward the cell body. Both cell extension and retraction critically depend on the organization and dynamics of the actin cytoskeleton, and the small, monomeric GTPases Rac...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Hemkemeyer, Sandra A., Vollmer, Veith, Schwarz, Vera, Lohmann, Birgit, Honnert, Ulrike, Taha, Muna, Schnittler, Hans-Joachim, Bähler, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949024/
https://ncbi.nlm.nih.gov/pubmed/33268376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013623
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