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Local Myo9b RhoGAP activity regulates cell motility

To migrate, cells assume a polarized morphology, extending forward with a leading edge with their trailing edge retracting back toward the cell body. Both cell extension and retraction critically depend on the organization and dynamics of the actin cytoskeleton, and the small, monomeric GTPases Rac...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Hemkemeyer, Sandra A., Vollmer, Veith, Schwarz, Vera, Lohmann, Birgit, Honnert, Ulrike, Taha, Muna, Schnittler, Hans-Joachim, Bähler, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949024/
https://ncbi.nlm.nih.gov/pubmed/33268376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013623
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