Local Myo9b RhoGAP activity regulates cell motility

To migrate, cells assume a polarized morphology, extending forward with a leading edge with their trailing edge retracting back toward the cell body. Both cell extension and retraction critically depend on the organization and dynamics of the actin cytoskeleton, and the small, monomeric GTPases Rac...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Hemkemeyer, Sandra A., Vollmer, Veith, Schwarz, Vera, Lohmann, Birgit, Honnert, Ulrike, Taha, Muna, Schnittler, Hans-Joachim, Bähler, Martin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949024/
https://ncbi.nlm.nih.gov/pubmed/33268376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013623
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