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Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development
African swine fever, caused by the African swine fever virus (ASFV), is among the most significant swine diseases. There are currently no effective treatments against ASFV. ASFV contains a gene encoding a dUTPase (E165R), which is required for viral replication in swine macrophages, making it an att...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948977/ https://ncbi.nlm.nih.gov/pubmed/33139328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014005 |
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