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African Swine Fever Virus dUTPase Is a Highly Specific Enzyme Required for Efficient Replication in Swine Macrophages

The African swine fever virus (ASFV) gene E165R, which is homologous to dUTPases, has been characterized. A multiple alignment of dUTPases showed the conservation in ASFV dUTPase of the motifs that define this protein family. A biochemical analysis of the purified recombinant enzyme showed that the...

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Detalhes bibliográficos
Main Authors: Oliveros, Mariano, García-Escudero, Ramón, Alejo, Alí, Viñuela, Eladio, Salas, María L., Salas, José
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112924/
https://ncbi.nlm.nih.gov/pubmed/10515998
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