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African Swine Fever Virus dUTPase Is a Highly Specific Enzyme Required for Efficient Replication in Swine Macrophages

The African swine fever virus (ASFV) gene E165R, which is homologous to dUTPases, has been characterized. A multiple alignment of dUTPases showed the conservation in ASFV dUTPase of the motifs that define this protein family. A biochemical analysis of the purified recombinant enzyme showed that the...

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Hlavní autoři: Oliveros, Mariano, García-Escudero, Ramón, Alejo, Alí, Viñuela, Eladio, Salas, María L., Salas, José
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC112924/
https://ncbi.nlm.nih.gov/pubmed/10515998
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