Acquired deficiency of peroxisomal dicarboxylic acid catabolism is a metabolic vulnerability in hepatoblastoma

Metabolic reprogramming provides transformed cells with proliferative and/or survival advantages. Capitalizing on this therapeutically, however, has been only moderately successful because of the relatively small magnitude of these differences and because cancers may further adapt their metabolism t...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Wang, Huabo, Lu, Jie, Chen, Xiaoguang, Schwalbe, Marie, Gorka, Joanna E., Mandel, Jordan A., Wang, Jinglin, Goetzman, Eric S., Ranganathan, Sarangarajan, Dobrowolski, Steven F., Prochownik, Edward V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948956/
https://ncbi.nlm.nih.gov/pubmed/33450224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100283
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