Complement receptor 3 mediates both sinking phagocytosis and phagocytic cup formation via distinct mechanisms

A long-standing hypothesis is that complement receptors (CRs), especially CR3, mediate sinking phagocytosis, but evidence is lacking. Alternatively, CRs have been reported to induce membrane ruffles or phagocytic cups, akin to those induced by Fcγ receptors (FcγRs), but the details of these events a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Walbaum, Stefan, Ambrosy, Benjamin, Schütz, Paula, Bachg, Anne C., Horsthemke, Markus, Leusen, Jeanette H.W., Mócsai, Attila, Hanley, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948798/
https://ncbi.nlm.nih.gov/pubmed/33839682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100256
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