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Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor–mediated chemotaxis

G protein–coupled receptor signaling is required for the navigation of immune cells along chemoattractant gradients. However, chemoattractant receptors may couple to more than one type of heterotrimeric G protein, each of which consists of a Gα, Gβ, and Gγ subunit, making it difficult to delineate t...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: van den Bos, Esther, Ambrosy, Benjamin, Horsthemke, Markus, Walbaum, Stefan, Bachg, Anne C., Wettschureck, Nina, Innamorati, Giulio, Wilkie, Thomas M., Hanley, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261795/
https://ncbi.nlm.nih.gov/pubmed/32332099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011984
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