Complement receptor 3 mediates both sinking phagocytosis and phagocytic cup formation via distinct mechanisms

A long-standing hypothesis is that complement receptors (CRs), especially CR3, mediate sinking phagocytosis, but evidence is lacking. Alternatively, CRs have been reported to induce membrane ruffles or phagocytic cups, akin to those induced by Fcγ receptors (FcγRs), but the details of these events a...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Walbaum, Stefan, Ambrosy, Benjamin, Schütz, Paula, Bachg, Anne C., Horsthemke, Markus, Leusen, Jeanette H.W., Mócsai, Attila, Hanley, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948798/
https://ncbi.nlm.nih.gov/pubmed/33839682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100256
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