A general chemical crosslinking strategy for structural analyses of weakly interacting proteins applied to preTCR–pMHC complexes

T lymphocytes discriminate between healthy and infected or cancerous cells via T-cell receptor-mediated recognition of peptides bound and presented by cell-surface-expressed major histocompatibility complex molecules (MHCs). Pre-T-cell receptors (preTCRs) on thymocytes foster development of αβT lymp...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Mizsei, Réka, Li, Xiaolong, Chen, Wan-Na, Szabo, Monika, Wang, Jia-Huai, Wagner, Gerhard, Reinherz, Ellis L., Mallis, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948749/
https://ncbi.nlm.nih.gov/pubmed/33837736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100255
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