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Codification of bidentate pMHC interaction with TCR and co-receptor

A 1983 Immunology Today rostrum hypothesized that each T cell has two recognition units: a TCR complex which binds antigen associated with a polymorphic region of an MHC molecule (pMHC) and a CD4 or CD8 molecule which bind to a conserved region of that same MHC gene product (class II or I, respectiv...

詳細記述

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書誌詳細
出版年:Trends Immunol
主要な著者: Reinherz, Ellis L., Wang, Jia-huai
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420642/
https://ncbi.nlm.nih.gov/pubmed/25818864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.03.004
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