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Microfluidic platform for characterizing TCR–pMHC interactions

The physical characteristics of the T cell receptor (TCR)–peptide-major histocompatibility complex (pMHC) interaction are known to play a central role in determining T cell function in the initial stages of the adaptive immune response. State-of-the-art assays can probe the kinetics of this interact...

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Dettagli Bibliografici
Pubblicato in:Biomicrofluidics
Autori principali: Stockslager, Max A., Bagnall, Josephine Shaw, Hecht, Vivian C., Hu, Kevin, Aranda-Michel, Edgar, Payer, Kristofor, Kimmerling, Robert J., Manalis, Scott R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: AIP Publishing LLC 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685811/
https://ncbi.nlm.nih.gov/pubmed/29204244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5002116
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