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Molecular Dynamics Simulations Reveal Canonical Conformations in Different pMHC/TCR Interactions

The major defense system against microbial pathogens in vertebrates is the adaptive immune response and represents an effective mechanism in cancer surveillance. T cells represent an essential component of this complex system. They can recognize myriads of antigens as short peptides (p) originated f...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Alba, Josephine, Di Rienzo, Lorenzo, Milanetti, Edoardo, Acuto, Oreste, D’Abramo, Marco
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226950/
https://ncbi.nlm.nih.gov/pubmed/32290289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040942
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