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Quantitative Characterization of Binding Pockets and Binding Complementarity by Means of Zernike Descriptors

[Image: see text] In this work, we describe the application of the Zernike formalism to quantitatively characterize the binding pockets of two sets of biologically relevant systems. Such an approach, when applied to molecular dynamics trajectories, is able to pinpoint the subtle differences between...

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Bibliografiske detaljer
Udgivet i:J Chem Inf Model
Main Authors: Di Rienzo, Lorenzo, Milanetti, Edoardo, Alba, Josephine, D’Abramo, Marco
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997106/
https://ncbi.nlm.nih.gov/pubmed/32050068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.9b01066
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