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SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1
Inducible degrader of the low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase mediating degradation of low-density lipoprotein (LDL) receptor (LDLR). IDOL also controls its own stability through autoubiquitination, primarily at lysine 293. Whether IDOL may undergo other forms of posttr...
Tallennettuna:
| Julkaisussa: | J Biol Chem |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948399/ https://ncbi.nlm.nih.gov/pubmed/33154164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015420 |
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