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Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2
The small ubiquitin-related modifier (SUMO) system is essential for smooth progression of cell cycle at the G2/M phase. Many centromeric proteins are reversibly SUMOylated to ensure proper chromosome segregation at the mitosis. SUMOylation of centromeric Origin Recognition Complex subunit 2 (ORC2) a...
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| Publié dans: | Oncotarget |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5642542/ https://ncbi.nlm.nih.gov/pubmed/29050267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19594 |
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