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Repression of eEF2 kinase improves deficits in novel object recognition memory in aged mice.

The normal aging process is commonly associated with mild cognitive deficits including memory decline. Previous studies indicate a role of dysregulated mRNA translation capacity in cognitive defects associated with aging and aging-related diseases, including hyperphosphorylation of eukaryotic elonga...

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Pubblicato in:Neurobiol Aging
Autori principali: Gosrani, Saahj, Jester, Hannah, Zhou, Xueyan, Ryazanov, Alexey, Ma, Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948257/
https://ncbi.nlm.nih.gov/pubmed/32810756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.07.016
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