Liver derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis

BACKGROUND: Fibroblast Growth Factor 21 (FGF21) is expressed in several metabolically active tissues, including liver, fat and acinar pancreas, and has pleiotropic effects on metabolic homeostasis. The dominant source of FGF21 in the circulation is the liver. OBJECTIVE AND METHODS: To analyze the ph...

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Détails bibliographiques
Publié dans:Endocrine
Auteurs principaux: Watanabe, Mikiko, Singhal, Garima, Fisher, ffolliott M, Beck, Thomas C, Morgan, Donald A, Socciarelli, Fabio, Mather, Marie L, Risi, Renata, Bourke, Jared, Rahmouni, Kamal, McGuinness, Owen P., Flier, Jeffrey S, Maratos-Flier, Eleftheria
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948212/
https://ncbi.nlm.nih.gov/pubmed/31728756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-019-02124-3
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