Liver derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis

BACKGROUND: Fibroblast Growth Factor 21 (FGF21) is expressed in several metabolically active tissues, including liver, fat and acinar pancreas, and has pleiotropic effects on metabolic homeostasis. The dominant source of FGF21 in the circulation is the liver. OBJECTIVE AND METHODS: To analyze the ph...

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Detalhes bibliográficos
Publicado no:Endocrine
Main Authors: Watanabe, Mikiko, Singhal, Garima, Fisher, ffolliott M, Beck, Thomas C, Morgan, Donald A, Socciarelli, Fabio, Mather, Marie L, Risi, Renata, Bourke, Jared, Rahmouni, Kamal, McGuinness, Owen P., Flier, Jeffrey S, Maratos-Flier, Eleftheria
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948212/
https://ncbi.nlm.nih.gov/pubmed/31728756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-019-02124-3
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