Effects of Obesity and Insulin on Tissue-Specific Recycling Between Cortisol and Cortisone in Men

CONTEXT: 11β-Hydroxysteroid dehydrogenase 1 (11βHSD1) reduces inert cortisone into active cortisol but also catalyzes reverse dehydrogenase activity. Drivers of cortisol/cortisone equilibrium are unclear. With obesity, 11βHSD1 transcripts are more abundant in adipose, but the consequences for oxidat...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Anderson, Anna J, Andrew, Ruth, Homer, Natalie Z M, Hughes, Katherine A, Boyle, Luke D, Nixon, Mark, Karpe, Fredrik, Stimson, Roland H, Walker, Brian R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947841/
https://ncbi.nlm.nih.gov/pubmed/33270115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa896
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