SAT-009 Proof of Concept That Corticosterone Has a Higher Therapeutic Index Than Hydrocortisone in Patients with Congenital Adrenal Hyperplasia

Congenital adrenal hyperplasia (CAH) is associated with poor health outcomes. This is, in part, because doses of glucocorticoid which are sufficient to suppress excess adrenal androgens are also associated with adverse metabolic effects such as insulin resistance. This toxicity occurs with efficacio...

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Vydáno v:J Endocr Soc
Hlavní autoři: Kyle, Catriona, Boyle, Luke, Nixon, Mark, Homer, Natalie, Andrew, Ruth, Freel, Marie, Stimson, Roland, Walker, Brian
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
Témata:
Steroid Hormones and Receptors
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552504/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-009
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