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Exploring Protein Space: From Hydrolase to Ligase by Substitution
The understanding of how proteins evolve to perform novel functions has long been sought by biologists. In this regard, two homologous bacterial enzymes, PafA and Dop, pose an insightful case study, as both rely on similar mechanistic properties, yet catalyze different reactions. PafA conjugates a s...
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| Vydáno v: | Mol Biol Evol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7947786/ https://ncbi.nlm.nih.gov/pubmed/32870983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa215 |
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