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Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes
The lipid phosphatidylinositol-3-phosphate (PI3P) is a regulator of two fundamental but distinct cellular processes, endocytosis and autophagy, so its generation needs to be under precise temporal and spatial control. PI3P is generated by two complexes that both contain the lipid kinase VPS34: compl...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7946940/ https://ncbi.nlm.nih.gov/pubmed/33692360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21695-2 |
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