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Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes
The lipid phosphatidylinositol-3-phosphate (PI3P) is a regulator of two fundamental but distinct cellular processes, endocytosis and autophagy, so its generation needs to be under precise temporal and spatial control. PI3P is generated by two complexes that both contain the lipid kinase VPS34: compl...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7946940/ https://ncbi.nlm.nih.gov/pubmed/33692360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21695-2 |
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