Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation

T effector cells promote inflammation in asthmatic patients and both Th2 and Th17 CD4 T cells have been implicated in severe forms of the disease. The metabolic phenotypes and dependencies of these cells, however, remain poorly understood in the regulation of airway inflammation. Here we show the br...

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Publicado no:J Immunol
Main Authors: Healey, Diana C. Contreras, Cephus, Jacqueline Y., Barone, Sierra M., Chowdhury, Nowrin U., Dahunsi, Debolanle O., Madden, Matthew Z., Ye, Xiang, Yu, Xuemei, Olszewski, Kellen, Young, Kirsten, Gerriets, Valerie A., Siska, Peter J., Dworski, Ryszard, Hemler, Jonathan, Locasale, Jason W., Poyurovsky, Masha V., Peebles, R. Stokes, Irish, Jonathan M., Newcomb, Dawn C., Rathmell, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946768/
https://ncbi.nlm.nih.gov/pubmed/33558372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2001029
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