Single-cell analysis by mass cytometry reveals metabolic states of early activated CD8(+) T cells during the primary immune response

Memory T cells are thought to rely on oxidative phosphorylation and short-lived effector T cells on glycolysis. Here, we investigated how T cells arrive at these states during an immune response. To understand the metabolic state of rare, early activated T cells, we adapted mass cytometry to quantif...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Levine, Lauren S., Hiam-Galvez, Kamir J., Marquez, Diana M., Tenvooren, Iliana, Madden, Matthew Z., Contreras, Diana C., Dahunsi, Debolanle O., Irish, Jonathan M., Oluwole, Olalekan O., Rathmell, Jeffrey C., Spitzer, Matthew H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046726/
https://ncbi.nlm.nih.gov/pubmed/33705706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.02.018
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