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Systemic dysfunction and plasticity of the immune macroenvironment in cancer models

Our understanding of the factors governing immune responses in cancer remains incomplete, limiting patient benefit. Here, we use mass cytometry to define the systemic immune landscape in response to tumor development across five tissues in eight mouse tumor models. Systemic immunity was dramatically...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Allen, Breanna M., Hiam, Kamir J., Burnett, Cassandra E., Venida, Anthony, DeBarge, Rachel, Tenvooren, Iliana, Marquez, Diana M., Cho, Nam Woo, Carmi, Yaron, Spitzer, Matthew H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384250/
https://ncbi.nlm.nih.gov/pubmed/32451499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-0892-6
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