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Proximal Tubule-Specific Deletion of AT(1a) Receptors in The Kidney Attenuates Circulating and Intratubular Angiotensin II-Induced Hypertension in PT-Agtr1a(−/−) Mice
The present study used a novel mouse model with proximal tubule-specific knockout of AT(1a) receptors in the kidney, PT-Agtr1a(−/−), to test the hypothesis that intratubular angiotensin II (Ang II) and AT(1a) receptors in the proximal tubules are required for maintaining normal blood pressure and th...
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| Udgivet i: | Hypertension |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7946728/ https://ncbi.nlm.nih.gov/pubmed/33641366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16336 |
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