Proximal tubule-specific deletion of the Na(+)/H(+) exchanger 3 promotes the pressure natriuresis response and lowers blood pressure in mice

The present study directly tested the hypothesis that deletion of the Na(+)/H(+) exchanger 3 (NHE3) selectively in the proximal tubules of the kidney lowers basal blood pressure by increasing the pressure natriuresis response in mice. Adult male and female, age-matched wild-type littermates (WT) and...

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Veröffentlicht in:Hypertension
Hauptverfasser: Li, Xiao C., Soleimani, Manoocher, Zhu, Dongmin, Rubera, Isabelle, Tauc, Michel, Zheng, Xiaowen, Zhang, Jianfeng, Chen, Xu, Zhuo, Jia L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309803/
https://ncbi.nlm.nih.gov/pubmed/30571224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.10884
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