Proximal Tubule-Specific Deletion of The NHE3 (Na(+)/H(+) Exchanger 3) in The Kidney Attenuates Angiotensin II-Induced Hypertension in Mice

The present study directly tested the hypothesis that the Na(+)/H(+) exchanger 3 (NHE3) in the proximal tubules of the kidney is required for the development of angiotensin II (ANG II)-induced hypertension using proximal tubule-specific NHE3 knockout mice (PT-Nhe3(−/−)). Specifically, PT-Nhe3(−/−) m...

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Publicat a:Hypertension
Autors principals: Li, Xiao C., Zhu, Dongmin, Chen, Xu, Zheng, Xiaowen, Zhao, Chunling, Zhang, Jianfeng, Soleimani, Manoocher, Rubera, Isabelle, Tauc, Michel, Zhou, Xinchun, Zhuo, Jia L.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685743/
https://ncbi.nlm.nih.gov/pubmed/31352824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13094
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