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Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Shaker potassium channel
Voltage-gated potassium (K(V)) channels can be opened by negatively charged resin acids and their derivatives. These resin acids have been proposed to attract the positively charged voltage-sensor helix (S4) toward the extracellular side of the membrane by binding to a pocket located between the lip...
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| Publicado en: | J Gen Physiol |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7944402/ https://ncbi.nlm.nih.gov/pubmed/33683319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012676 |
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