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Coupling stabilizers open K(V)1-type potassium channels

The opening and closing of voltage-gated ion channels are regulated by voltage sensors coupled to a gate that controls the ion flux across the cellular membrane. Modulation of any part of gating constitutes an entry point for pharmacologically regulating channel function. Here, we report on the disc...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Silverå Ejneby, Malin, Wallner, Björn, Elinder, Fredrik
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604479/
https://ncbi.nlm.nih.gov/pubmed/33051293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007965117
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