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Coupling stabilizers open K(V)1-type potassium channels

The opening and closing of voltage-gated ion channels are regulated by voltage sensors coupled to a gate that controls the ion flux across the cellular membrane. Modulation of any part of gating constitutes an entry point for pharmacologically regulating channel function. Here, we report on the disc...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Silverå Ejneby, Malin, Wallner, Björn, Elinder, Fredrik
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604479/
https://ncbi.nlm.nih.gov/pubmed/33051293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007965117
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