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Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation
Voltage-gated potassium channels open at depolarized membrane voltages. A prolonged depolarization causes a rearrangement of the selectivity filter which terminates the conduction of ions – a process called slow or C-type inactivation. How structural rearrangements in the voltage-sensor domain (VSD)...
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| Vydáno v: | Sci Rep |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899724/ https://ncbi.nlm.nih.gov/pubmed/27278891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27562 |
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