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Tracking a complete voltage-sensor cycle with metal-ion bridges

Voltage-gated ion channels open and close in response to changes in membrane potential, thereby enabling electrical signaling in excitable cells. The voltage sensitivity is conferred through four voltage-sensor domains (VSDs) where positively charged residues in the fourth transmembrane segment (S4)...

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Detalhes bibliográficos
Main Authors: Henrion, Ulrike, Renhorn, Jakob, Börjesson, Sara I., Nelson, Erin M., Schwaiger, Christine S., Bjelkmar, Pär, Wallner, Björn, Lindahl, Erik, Elinder, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365220/
https://ncbi.nlm.nih.gov/pubmed/22538811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116938109
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