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3(10)-Helix Conformation Facilitates the Transition of a Voltage Sensor S4 Segment toward the Down State

The activation of voltage-gated ion channels is controlled by the S4 helix, with arginines every third residue. The x-ray structures are believed to reflect an open-inactivated state, and models propose combinations of translation, rotation, and tilt to reach the resting state. Recently, experiments...

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Detalles Bibliográficos
Main Authors: Schwaiger, Christine S., Bjelkmar, Pär, Hess, Berk, Lindahl, Erik
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059565/
https://ncbi.nlm.nih.gov/pubmed/21402026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.003
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