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3(10)-Helix Conformation Facilitates the Transition of a Voltage Sensor S4 Segment toward the Down State
The activation of voltage-gated ion channels is controlled by the S4 helix, with arginines every third residue. The x-ray structures are believed to reflect an open-inactivated state, and models propose combinations of translation, rotation, and tilt to reach the resting state. Recently, experiments...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059565/ https://ncbi.nlm.nih.gov/pubmed/21402026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.003 |
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