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Lipoelectric Modification of Ion Channel Voltage Gating by Polyunsaturated Fatty Acids
Polyunsaturated fatty acids (PUFAs) have beneficial effects on epileptic seizures and cardiac arrhythmia. We report that ω-3 and ω-6 all-cis-PUFAs affected the voltage dependence of the Shaker K channel by shifting the conductance versus voltage and the gating charge versus voltage curves in negativ...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Biophysical Society
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517024/ https://ncbi.nlm.nih.gov/pubmed/18502799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.130757 |
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