Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl‐2/caspase‐3 pathway

Cachexia, characterized by loss of skeletal muscle mass and function, is estimated to inflict the majority of patients with oesophageal squamous cell carcinoma (ESCC) and associated with their poor prognosis. However, its underlying mechanisms remain elusive. Here, we developed an ESCC‐induced cache...

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Bibliografiske detaljer
Udgivet i:J Extracell Vesicles
Main Authors: Gao, Xiaohan, Wang, Yan, Lu, Fang, Chen, Xu, Yang, Di, Cao, Yiren, Zhang, Weimin, Chen, Jie, Zheng, Leilei, Wang, Guangchao, Fu, Ming, Ma, Liying, Song, Yongmei, Zhan, Qimin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944388/
https://ncbi.nlm.nih.gov/pubmed/33732415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12060
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