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Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl‐2/caspase‐3 pathway

Cachexia, characterized by loss of skeletal muscle mass and function, is estimated to inflict the majority of patients with oesophageal squamous cell carcinoma (ESCC) and associated with their poor prognosis. However, its underlying mechanisms remain elusive. Here, we developed an ESCC‐induced cache...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Extracell Vesicles
Egile Nagusiak: Gao, Xiaohan, Wang, Yan, Lu, Fang, Chen, Xu, Yang, Di, Cao, Yiren, Zhang, Weimin, Chen, Jie, Zheng, Leilei, Wang, Guangchao, Fu, Ming, Ma, Liying, Song, Yongmei, Zhan, Qimin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944388/
https://ncbi.nlm.nih.gov/pubmed/33732415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12060
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