Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl‐2/caspase‐3 pathway

Cachexia, characterized by loss of skeletal muscle mass and function, is estimated to inflict the majority of patients with oesophageal squamous cell carcinoma (ESCC) and associated with their poor prognosis. However, its underlying mechanisms remain elusive. Here, we developed an ESCC‐induced cache...

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Dades bibliogràfiques
Publicat a:J Extracell Vesicles
Autors principals: Gao, Xiaohan, Wang, Yan, Lu, Fang, Chen, Xu, Yang, Di, Cao, Yiren, Zhang, Weimin, Chen, Jie, Zheng, Leilei, Wang, Guangchao, Fu, Ming, Ma, Liying, Song, Yongmei, Zhan, Qimin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944388/
https://ncbi.nlm.nih.gov/pubmed/33732415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12060
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