Oncolytic effect of Midkine promoter–based conditionally replicating adenoviruses expressing EGFR siRNA in head and neck squamous cancer cell line T891

BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in head and neck squamous cell carcinomas (HNSCCs). Midkine expression is restricted in adult tissues but is increased in several malignant tumors, including HNSCCs. AIM: Here, we evaluated the antitumor effect of Midkine promoter–...

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Publicat a:Cancer Rep (Hoboken)
Autors principals: Uehara, Natsumi, Otsuki, Naoki, Kubo, Mie, Kitamoto, Junko, Kojima, Yasutaka, Teshima, Masanori, Shinomiya, Hirotaka, Shirakawa, Toshiro, Nibu, Ken‐ichi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941548/
https://ncbi.nlm.nih.gov/pubmed/32671980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1231
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