Oncolytic effect of Midkine promoter–based conditionally replicating adenoviruses expressing EGFR siRNA in head and neck squamous cancer cell line T891

BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in head and neck squamous cell carcinomas (HNSCCs). Midkine expression is restricted in adult tissues but is increased in several malignant tumors, including HNSCCs. AIM: Here, we evaluated the antitumor effect of Midkine promoter–...

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Detalhes bibliográficos
Publicado no:Cancer Rep (Hoboken)
Main Authors: Uehara, Natsumi, Otsuki, Naoki, Kubo, Mie, Kitamoto, Junko, Kojima, Yasutaka, Teshima, Masanori, Shinomiya, Hirotaka, Shirakawa, Toshiro, Nibu, Ken‐ichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941548/
https://ncbi.nlm.nih.gov/pubmed/32671980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1231
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