Oncolytic effect of Midkine promoter–based conditionally replicating adenoviruses expressing EGFR siRNA in head and neck squamous cancer cell line T891

BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in head and neck squamous cell carcinomas (HNSCCs). Midkine expression is restricted in adult tissues but is increased in several malignant tumors, including HNSCCs. AIM: Here, we evaluated the antitumor effect of Midkine promoter–...

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Detaylı Bibliyografya
Yayımlandı:Cancer Rep (Hoboken)
Asıl Yazarlar: Uehara, Natsumi, Otsuki, Naoki, Kubo, Mie, Kitamoto, Junko, Kojima, Yasutaka, Teshima, Masanori, Shinomiya, Hirotaka, Shirakawa, Toshiro, Nibu, Ken‐ichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941548/
https://ncbi.nlm.nih.gov/pubmed/32671980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1231
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